Affinity purification of human factor H on polypeptides derived from streptococcal m protein: enrichment of the Y402 variant.

Recent studies indicate that defective activity of complement factor H (FH) is associated with several human diseases, suggesting that pure FH may be used for therapy.Here, we describe a simple method to isolate human FH, based on the specific interaction Toner Originals between FH and the hypervariable region (HVR) of certain Streptococcus pyogene

read more


Mechanisms regulating the CRISPR-Cas systems

The CRISPR-Cas (Clustered Regularly Interspaced Short Palindromic Repeats- CRISPR associated proteins) is a prokaryotic system that enables sequence specific recognition and cleavage of nucleic acids.This is possible due to cooperation between CRISPR array which contains short fragments of DNA called spacers that are complimentary to the targeted n

read more

Incidence of Metastasis of Oral Squamous Cell Carcinoma in Submandibular Gland among N+ Cases of Neck Dissection: A Research Protocol

Introduction: Oral Squamous Cell Carcinoma (OSCC) is one of the most common malignant diseases of head and neck region.Management of OSCC involves removal of the Submandibular Gland (SMG) along with lymph nodes.The submandibular salivary gland is routinely removed, considering metastatic involvement from OSCC.Many studies showed there is no or rare

read more